Single peptide Vial strength 10 mg
PE-22-2810 mg
Explore the format, calculations, and schedules reported for this compound.
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Get to know the compound
PE-22-28, explained simply
A synthetic peptide derived from spadin, explored in models of neuroplasticity and behaviour.
Research area
TREK-1 ion channels, mood, and neuronal protection
How it works
Experimental blockade of TREK-1 channels is linked to changes in neuronal excitability and signaling.
Why it matters
This compound illustrates how ion-channel research explores new targets for mood disorders.
What has been observed
Antidepressant-like effects and neurogenesis markers have been described in preclinical models, without evidence of clinical efficacy in humans.
Effects and points to consider
Animal findings cannot predict effects, tolerability, or usefulness for people with mood disorders.
01 / Vial strength 10 mg
Reported data
Doses and cycles are presented for information and education only; they are not prescriptions or medical advice.
Reported vial strength and reconstitution
| Vial contents | 10 mg PE-22-28 |
|---|---|
| Final volume | 3 mL |
| Concentration | 3.33 mg/mL |
| One U-100 unit | 33.33 mcg in 0.01 mL |
Standard / Gradual Approach (3 mL = ~3.33 mg/mL)
| Week | Daily Dose (µg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 50 µg | 1.5 units (0.015 mL) |
| Weeks 3–4 | 100 µg | 3 units (0.03 mL) |
| Weeks 5–8 | 100 µg | 3 units (0.03 mL) |
| Weeks 9–12 (Optional) | 150 µg | 4.5 units (0.045 mL) |
| Weeks 13–16 (Optional) | 200 µg | 6 units (0.06 mL) |
Supplies needed
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Sterile alcohol swabs
SOURCES
Scientific references
Links reported by the source and selected by type. Their presence does not validate this page’s dosage data.